While NLH and PLO have some similarities, there are several elements that cause the games to play very differently. The strength of made hands and draws are evaluated very differently in PLO. Equity advantages are also much narrower than in NLH.
If you are completely new to PLO, read this quick primer on the rules of the game. There are some key differences compared to NLH (e.g. you have to play exactly 2 cards from your hand), so you’ll want to be up to speed.
While you can always announce “Pot” and have the dealer figure it out, it’s important to know how to determine “pot” to calculate fold equity and value. You will also want to know the max potential bet size if you are re-raised.
If you’re just starting out, you’ll want to have a few basic guidelines to anchor your play. In a game where the complexity of pre-flop and post-flop combinations (both yours and opponents) is increased substantially, having a solid starting strategy is a key to success.